Inwazja kryzysu opioidowego, który dotknął Kanadę w ostatniej dekadzie, skłoniła do ponownej oceny roli wszystkich opioidów, w tym kodeiny. Chociaż kodeina jest często postrzegana jako "łagodniejszy" opioid, dostępny w niektórych formach bez recepty lub z ograniczoną receptą, jej wszechobecność i potencjał uzależniający sprawiaj�

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